References regarding the above:

Campbell AW, Thrasher JD, Madison RA, Gray MR, Johnson A. 2003. Neural antibodies and neurophysiologic abnormalities in patients exposed to molds in water-damaged buildings. Arch Environ Health. 58:464-74.

Campbell AW, Thrasher JD, Gray MR, Vojdani A. 2004. Mold an mycotoxins: effects on neurological and immune systems in humans. Adv Appl Microbiol 55:375-406.

Crago BR, Grau MR, Nelson LA, Davis M, Arnold L, Thrasher JD. 2003. Psychological, neuropsychological, and electrocortical effects of mixed mold exposure. Arch Environ Health. 45:452-63.

Empting LD (2009)  Neurologic and neuropsychiatric syndromes features of mold and mycotoxin exposure. Toxicol Indust Health 25:577-81.

Dennis D, Robertson D, Curtis L, Black J (2009) Fungal exposure endocrinopathy in sinusitis with growth hormone deficiency:  Dennis-Robertson syndrome.  Toxicol Indust Health 25:66.9-80.

Gordon WA, Cantor JB. 2004. Diagnosis of cognitive impairment associated with exposure to mold. Adv. Appl Microbiol 55:361-74.

Gordon WA, Cantor JB, Johanning E, Charatz HJ, et al.  2004 Cognitive impairment associated with toxigenic fungal exposure: a replication and extension of previous findings. Appl Neurophysiol 11:85-74.

Gordon WA, Cantor RB, Spielman L, Ashman TA, Johanning E. 2006. Cognitive impairment associated with toxigenic fungal exposure: response to two critiques. Appl Neurophysiol 13:251-7.

Gray MR, Thrasher JD, Crago R, Madison RA, Arnold L, et al. 2003. Mixed mold mycotoxicosis: Immunological changes in humans following exposure in water-damaged buildings. Arch Environ Health 58:410-20.

Kilburn KH, 2003.  Indoor mold exposure associated with neurobehavioral and pulmonary impairment: a preliminary report. Arch Environ Health 58:390-8.

Kilburn. KH . 2004. Role of molds and mycotoxins in being sick in buildings. Adv Appl Microbiol. 55:339-59.

Kilburn KH (2009) Neurobehavioral and pulmonary impairment in 105 adults with indoor exposure to molds compare to 100 exposed to chemicals.  Toxicol Indust Health 25:681-92.

Kilburn KH, Thrasher JD, Immers NB (2009) Do terbutaline- and mold-associated impairments of the brain and lung relate to autism? Toxicol Indust Health 25:703-10.

Rea WJ. Didrikesen N, Simon TR, Pan Y, et al. 2003. Effects of toxic exposure to mold and mycotoxins in building-related illnesses. Arch Environ Health. 58:399-405.

Rea WJ, Pan Y, Griffiths B. 2009. The treatment of patients with mycotoxin-induced disease, Toxicol Indust Health 25:711-4.

       B.   Instillation of mycotoxins into the olfactory mucosa of rodents.  Satratoxin G, roridin A and aflatoxin B1 instilled into the olfactory area cause sensory olfactory neuron loss, nasal and brain inflammation, and neurotoxicity.  The mycotoxins are transported into the brain along the olfactory tract leading to inflammation and damage in the tract and the olfactory bulbs.  Tritium labelled aflatoxin B1 at 0.2, 1 or 20 ug was intranasally instilled in rats and followed by autoradiography and spectrometry.  The mycotoxin was bioactivated in the olfactory/nasal mucosa and transported along the olfactory tract to the bulbs.  Twenty-four hours after instillation the olfactory epithelium was disorganized and undulating with pyknotic nuclei, shrunken cytoplasm and transport of the labelled aflatoxin to the olfactory bulbs.  The pathology was still present at 5 days post instillation at 20 ug (Larsson and Tjalve, 2000).   Satratoxin G was instilled into the olfactory mucosa in mice at 5 and 25 ug/kg body weight.  
Apoptosis of olfactory neurons occurred along with the release of proinflammatory cytokines TNF-alpha, IL-6, IL-1 and MIP-2 in the nasal airways, ethmoid turbinates and olfactory bulbs.  Marked atrophy of the olfactory nerve and glomerular layers of the bulb were observed (Islam et al., 2006a, b).  Similarly, roridin A instilled into the olfactory mucosa of mice at 500 ug/kg body weight induced apoptosis of olfactory neurons, atrophy of the olfactory epithelium and olfactory bulbs.   The kinetics of the reported pathology was potentiated by the simultaneous exposure to lipopolysaccharide (Islam et al., 2007).   Also, lipopolysaccharides enhance the hepatoxicity of aflatoxin B1 in rats (Barton et al., 2001; Luyendyk et al., 2002, 2003).  Finally, C-14 aromatic carboxylic acids are transferred